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. 2024 Apr 25;14:9511. doi: 10.1038/s41598-024-59674-4

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Abundances of bacterial communities changes at phylum level and related metabolic pathways with OTC treatment. (A–C) Relative abundances of bacterial phyla in four groups. Each color represents a phylum. No significantly changed phyla are merged in an “Others with N.S.” category. (D) KEGG pathways associated with significantly different abundances in the bacterial metagenomics profiles of BT and AT groups. The bars represent the proportion of each category in the data. Category differences with a P < 0.05 were considered to be significant.