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. 2024 Apr 25;10:193. doi: 10.1038/s41420-024-01946-z

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — A Tube formation assays to evaluate the effects of the miR-134-5p/ITGB1/MMP2 axis on VM. Scale bar, 200 μm. B Transwell assays to evaluate the effects of the miR-134-5p/ITGB1/MMP2 axis on migration and invasion. Scale bar, 100 μm. C CCK-8 assay were to evaluate the effect of miR-134-5p/ITGB1/MMP2 axis on cell proliferation. D Protein levels of p-PI3K, PI3K, p-Akt, and Akt, shown by western blotting. Statistics using one-way ANOVA with Tukey’s test. The data represent means ± SD. *p < 0.05; **p < 0.01; ***p < 0.001.