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. 2024 Apr 25;10:193. doi: 10.1038/s41420-024-01946-z

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — A Protein levels of p-PI3K, PI3K, p-Akt, and Akt in different groups. B CCK-8 assay to evaluate the effects of the miR-134-5p/PI3K/Akt axis on cell proliferation. C Transwell assays to evaluate the effects of the miR-134-5p/PI3K/Akt axis on migration and invasion. Scale bar, 100 μm. D Tube formation assays to evaluate the effects of the miR-134-5p/PI3K/Akt axis on VM. Statistics using one-way ANOVA with Tukey’s test. Scale bar, 200 μm. The data represent means ± SD. **p < 0.01; ***p < 0.001.