Table 1.
Descriptive data of the cohort, stratified by sex.
| Mixed cohort (N = 139) | Women (N = 65) | Men (N = 74) | P-value | |
|---|---|---|---|---|
| Age, median (interquartile range) | 54 years (42; 64) | 54 years (42; 65) | 54 years (42; 63) | 0.26 |
| Intracranial pressure, mean (95% CI) | 15 mmHg (14; 16) | 15 mmHg (13; 18) | 15 mmHg (13; 17) | 0.88 |
| Intraventricular measurement of intracranial pressure, n (%) | 94 (68%) | 51 (78%) | 43 (58%) | 0.01 |
| Intraparenchymal measurement of intracranial pressure, n (%) | 45 (32%) | 14 (22%) | 31 (42%) | 0.01 |
| ONSDexta, mean (95% CI) | 6.7 mm (6.6; 6.7) | 6.5 mm (6.4; 6.6) | 6.8 mm (6.7; 6.9) | < 0.001 |
| ONSDintb, mean (95% CI) | 5.2 (5.1; 5.2) | 5.1 mm (5.1; 5.2) | 5.2 mm (5.1; 5.3) | 0.08 |
| Primary diagnosis | ||||
| Subarachnoid hemorrhage, n (%) | 63 (45%) | 38 (59%) | 25 (34%) | < 0.001 |
| Traumatic brain injury, n (%) | 29 (21%) | 9 (14%) | 20 (27%) | 0.06 |
| Intracerebral hematoma, n (%) | 21 (15%) | 9 (14%) | 12 (16%) | 0.81 |
| Other diagnosis, n (%) | 26 (19%) | 9 (14%) | 17 (23%) | 0.20 |
| Comorbidities | ||||
| Cardiovascular disease, n (%) | 11 (8%) | 5 (8%) | 6 (8%) | > 0.99 |
| Asthma or chronic obstructive pulmonary disease, n (%) | 13 (9%) | 9 (14%) | 4 (6%) | 0.14 |
| Diabetes, n (%) | 12 (9%) | 6 (9%) | 6 (8%) | > 0.99 |
| Intensive care treatments | ||||
| Norepinephine infusion, n (%) | 110 (79%) | 51 (78%) | 59 (80%) | 0.91 |
| Opioid infusion, n (%) | 111 (80%) | 50 (77%) | 61 (82%) | 0.53 |
| Propofol infusion, n (%) | 118 (85%) | 56 (86%) | 62 (84%) | 0.81 |
| Midazolam infusion, n (%) | 45 (32%) | 15 (23%) | 30 (41%) | 0.05 |
| Pentothal infusion, n (%) | 9 (6%) | 3 (5%) | 6 (8%) | 0.50 |
aOptic nerve sheath diameter measured external of the dura mater.
bOptic nerve sheath diameter measured internal of the dura mater.