Table 4.

Diagnostic characteristics and optimal cut-offs for ONSD predictors of elevated ICP.

Sex, predictor	Cut-off	Sensa	Specb	PPVc	NPVd	LR+e	LR−f	Accg
Female, ONSDexth	6.75	0.71	0.74	0.36	0.93	2.7	0.39	0.73
Male, ONSDext	6.80	0.59	0.58	0.22	0.86	1.4	0.71	0.53
Female, ONSDinti	5.34	0.67	0.75	0.35	0.92	2.7	0.44	0.73
Male, ONSDint	5.45	0.44	0.75	0.27	0.85	1.8	0.75	0.70
Female, ONSDext/EDj	0.30	0.81	0.84	0.50	0.93	5.1	0.23	0.83
Male, ONSDext/ED	0.28	0.85	0.35	0.21	0.83	1.3	0.43	0.67
Female, ONSDint/EDk	0.24	0.62	0.93	0.65	0.92	8.9	0.47	0.88
Male, ONSDint/ED	0.22	0.74	0.51	0.24	0.88	1.5	0.51	0.57

^aSensitivity.

^bSpecificity.

^cPositive predictive value.

^dNegative predictive value.

^ePositive likelihood ratio.

^fNegative likelihood ratio.

^gAccuracy.

^hONSD measured external of the dura mater.

ⁱONSD measured internal of the dura mater.

^jONSD measured external of the dura mater, divided by eye diameter.

^kONSD measured internal of the dura mater, divided by eye diameter.