Table 2.
Most enriched MONARCH and disease terms in RNS secretomes.
| Name | pValue | Genes from input | Genes in annotation | |
|---|---|---|---|---|
| Monarch | ||||
| HP:0001075 | Atrophic scars | 4.44e–10 | 8 | 35 |
| HP:0000977 | Soft skin | 1.97e–08 | 7 | 35 |
| HP:0002808 | Kyphosis | 1.97e–08 | 13 | 406 |
| HP:0100699 | Scarring | 1.97e–08 | 10 | 162 |
| HP:0001058 | Poor wound healing | 3.95e–08 | 6 | 20 |
| HP:0000592 | Blue sclerae | 4.01e–08 | 8 | 83 |
| HP:0004348 | Abnormality of bone mineral density | 4.01e–08 | 13 | 469 |
| HP:0008780 | Congenital bilateral hip dislocation | 7.08e–08 | 5 | 8 |
| HP:0002645 | Wormian bones | 7.62e–08 | 7 | 54 |
| HP:0002644 | Abnormality of pelvic girdle bone morphology | 1.21e–07 | 12 | 419 |
| HP:0002814 | Abnormality of the lower limb | 1.27e–07 | 19 | 1509 |
| HP:0000974 | Hyperextensible skin | 1.33e–07 | 7 | 63 |
| HP:0011025 | Abnormal cardiovascular system physiology | 1.63e–07 | 17 | 1168 |
| HP:0001030 | Fragile skin | 2.01e–07 | 6 | 34 |
| HP:0001374 | Congenital hip dislocation | 2.60e–07 | 7 | 72 |
| Disease | ||||
| DOID:65 | Connective tissue disease | 1.58e–12 | 19 | 715 |
| DOID:17 | Musculoskeletal system disease | 7.68e–11 | 20 | 1074 |
| DOID:13359 | Ehlers-Danlos syndrome | 5.95e–08 | 6 | 23 |
| DOID:0080001 | Bone disease | 1.17e–06 | 12 | 523 |
| DOID:7 | Disease of anatomical entity | 1.17e–06 | 29 | 4452 |
| DOID:12347 | Osteogenesis imperfecta | 8.66e–06 | 5 | 30 |