REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
APC-Cy7 rat anti-mouse CD326 clone G8.8 (EpCAM)	BioLegend	Cat# 118217; RRID: AB_1501158
PE-Cy7 rat anti-human CD49f clone GoH3	BioLegend	Cat# 313622; RRID: AB_2561705
eFluor™ 450 rat anti-mouse CD31 clone 390	ThermoFisher	Cat# 48-0311-82; RRID: AB_10598807
eFluor™ 450 rat anti-mouse CD45 clone 30-F11	ThermoFisher	Cat# 48-0451-82; RRID: AB_1518806
eFluor™ 450 rat anti-mouse TER-119 clone TER-119	ThermoFisher	Cat# 48-5921-82; RRID: AB_1518808
APC Mouse Anti-Mouse CD36 clone CRF D-2712	BD Biosciences	Cat# 562744; RRID: AB_2737763
APC rat anti-mouse CD326 clone G8.8 (EpCAM)	BioLegend	Cat# 118214; RRID: AB_1134102
PE Mouse Anti-Mouse CD36 clone CRF D-2712	BD Biosciences	Cat# 562702; RRID: AB_2737732
Critical commercial assays
MTR CM-H2Xros	ThermoFisher	M7513
BODIPY™ FL C12	ThermoFisher	D3822
Deposited data
Raw mass spectrometry data	This study	MassIVE: MSV000092829
Processed mass spectrometry data	This study	See Table S4
Experimental models: Cell lines
Human: Hs 578T	ATCC	HTB-126
Human: HCC1187	ATCC	CRL-2322
Human: MCF10A	ATCC	CRL-10317
Human: MDA-MB-157	ATCC	HTB-24
Experimental models: Organisms/strains
Mouse: 8- to 12-week-old virgin female FVB wild-type mice	The Jackson Laboratory or Charles River	001800 or 207
Software and algorithms
MSFragger (v.3.8) run using FragPipe (v.20.0)	Kong et al.46 and Teo et al.47	N/A
ProteinProphet	Nesvizhskii et al.48	N/A
Percolator	Käll et al.49	N/A
IonQuant v.1.9.8:	Yu et al.50	N/A
Philosopher v.5.0.0	da Veiga Leprevost et al.51	N/A
Other
Orbitrap Fusion Tribrid mass spectrometer	Thermo Scientific	N/A
EASY-nLC 1000 HPLC system	Thermo Scientific	N/A
Teflon-coated microscope slides	Tekdon	N/A
Microscrope slide holder	This study	N/A
ImageStream AMNIS MKII imaging flow cytometer	Cytek Biosciences	N/A
FACS ARIA Fusion Flow Cytometer	BD Biosciences	N/A