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. 2024 Apr 12;15:1330228. doi: 10.3389/fimmu.2024.1330228

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Copyright © 2024 Kim, Lee, Han, Park, Han, Na, Kim, Yang, Baek, Kim, Hwang, Lee, Kang, Hong, Lim, Lee, Kim, Cho and Pyo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential AhR expression based on different cell types and locations. (A) PCA plot distinguishing the three clusters from each group. (B) PCA plot distinguishing the five cancer types from each group. (C) PC1 table displaying the AhR expression in different locations, including the cytosol vs. nucleus, tumor nest (TN) vs. stroma (ST), and different markers (Pan-CK, CD68, CD4/8, and Treg). (D) Bar graph showing the AhR expression in cancer cell nucleus and stromal Treg nucleus in three different clusters. (E) Pie chart representing the distribution of the five cancer types within the three different clusters. (F) Violin plot portraying the AhR expression in the cytosol vs. nucleus in the five cancer types. (G) Bar graph depicting the AhR expression in the tumor and immune cell types in the five cancer types. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.