Figure 7. Comparison of ARRDC3 residues near the C182Y position in the Gnathostomes.

TMRCA is the estimated time to the most recent common ancestor in millions of years (Hedges et al., 2015). The full length ARRDC3 protein is 414 residues in cattle and most of the Amniota species. The letters are IUPAC/IUBMB codes for amino acids. The dots are amino acid residues identical to those in cattle.