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. 2022 Apr 1;11:385. [Version 1] doi: 10.12688/f1000research.109488.1

PMC11046187.1; 2022 Apr 1
PMC11046187.2; 2024 Mar 4

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Copyright: © 2022 Heaton MP et al.

This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — Two-SNPs were used for identifying feedlot cattle with homozygous risk alleles (BovineHD0700027239 [ ARRDC3] and BovineHD0300024308 [ NFIA]). Bovine cohorts: USMARC beef cattle diversity panel v2.9 (19 breeds (Heaton et al., 2016), Kansas feedlot calves persistently infected with bovine viral diarrhea virus (BVDV PI (Workman et al., 2016), pen matched BCHF controls (this study), BCHF cases (this study), independent BCHF validation cases (this study). The BCHF validation cases were collected by pen riders experienced in BCHF diagnosis, however, they were not confirmed at necropsy by veterinarians and researchers. All 204 of the BCHF case-control cattle tested negative for BVDV, and thus were not persistently infected with BVDV.