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. 2024 Mar 4;11:385. Originally published 2022 Apr 1. [Version 2] doi: 10.12688/f1000research.109488.2

Table 3. ARRDC3 and NFIA genotype configurations, expected disease risk, and relative breeding rank.

Possible risk allele configurations ( ARRDC3, NFIA) a Total combined risk alleles Disease risk (1 to 28 scale) b Probability of risk allele transmission (%) Breeding rank c
0,0 0 1x 0 1
1,0 1 1x 25 2
0,1 1 1x 25 2
1,1 2 1x 50 3
2,0 2 8x 50 3
0,2 2 8x 50 3
2,1 3 8x 75 4
1,2 3 8x 75 4
2,2 4 28x 100 5
a

Diploid combinations of risk alleles for each gene with markers BovineHD0700027239 ( ARRDC3) and BovineHD0300024308 ( NFIA).

b

The risk of developing BCHF in a feedlot with animals and environments like those described here.

c

The relative BCHF breeding rank of an animal based on having risk genotypes for ARRDC3 and NFIA from best (1) to worst (5).