Table 3. ARRDC3 and NFIA genotype configurations, expected disease risk, and relative breeding rank.
Possible risk allele configurations ( ARRDC3, NFIA) a | Total combined risk alleles | Disease risk (1 to 28 scale) b | Probability of risk allele transmission (%) | Breeding rank c |
---|---|---|---|---|
0,0 | 0 | 1x | 0 | 1 |
1,0 | 1 | 1x | 25 | 2 |
0,1 | 1 | 1x | 25 | 2 |
1,1 | 2 | 1x | 50 | 3 |
2,0 | 2 | 8x | 50 | 3 |
0,2 | 2 | 8x | 50 | 3 |
2,1 | 3 | 8x | 75 | 4 |
1,2 | 3 | 8x | 75 | 4 |
2,2 | 4 | 28x | 100 | 5 |
Diploid combinations of risk alleles for each gene with markers BovineHD0700027239 ( ARRDC3) and BovineHD0300024308 ( NFIA).
The risk of developing BCHF in a feedlot with animals and environments like those described here.
The relative BCHF breeding rank of an animal based on having risk genotypes for ARRDC3 and NFIA from best (1) to worst (5).