(A) Serum iron measured by colorimeteric iron assay. (B) Analysis of RBC, MCV, HB, and HCT from 48 month old Hif2αfl/fl and Hif2αΔmφ (n = 7-9 per group). (C) Analysis of WBC, Monocytes, Neutrophils, Lymphocytes from 8 month old Hif2αfl/fl and Hif2αΔmφ (n = 7–9 per group). Data represent the mean ± SEM. Significance was determined by unpaired t test. *P < 0.05, ***P < 0.001, and ****P < 0.0001 versus the Hif2αfl/fl group.