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. 2024 Apr 25;142(6):560–567. doi: 10.1001/jamaophthalmol.2024.0801

Table 2. One-Year Change in Outcomes.

Characteristic Mean change (SD) Mean difference (95% CI) P value
Control (n = 168) Treatment (n = 168)
All children (n = 336)
AL, mm 0.26 (0.16) −0.11 (0.10) 0.37 (0.34 to 0.40) <.001
SER, D −0.65 (0.33) 0.24 (0.27) −0.89 (−0.95 to −0.83) <.001
ChT, μm −22.26 (12.05) 16.46 (18.15) −38.72 (−42.02 to −35.41) <.001
UDVA −0.09 (0.32) 0.02 (0.36) −0.11 (−0.18 to −0.04) <.001
IOP, mm Hg 0.22 (1.53) 0.63 (1.88) −0.41 (−1.21 to 0.39) .31
CCT, μm 2.49 (4.61) 6.58 (5.54) −4.09 (−14.75 to 6.57) .45
AD, mm 0.08 (0.13) 0.06 (0.15) 0.01 (−0.02 to 0.05) .38
LT, mm −0.04 (0.12) −0.04 (0.12) −0.01 (−0.03 to 0.02) .75
K1, D −0.09 (0.75) −0.16 (0.77) 0.07 (−0.09 to 0.23) .38
K2, D −0.04 (0.71) −0.028 (0.75) −0.01 (−0.17 to 0.14) .86
Children with myopia (n = 224)
AL, mm 0.27 (0.14) −0.12 (0.11) 0.39 (0.35 to 0.43) <.001
SER, D −0.71 (0.30) 0.26 (0.29) −0.97 (−1.05 to −0.89) <.001
ChT, μm −23.38 (9.24) 17.88 (19.42) −41.26 (−45.26 to −37.26) <.001
UDVA −0.06 (0.29) 0.034 (0.37) −0.09 (−0.18 to −0.01) <.001
Children without myopia (n = 112)
AL, mm 0.24 (0.18) −0.09 (0.08) 0.33 (0.28 to 0.38) <.001
SER, D −0.51 (0.35) 0.20 (0.22) −0.71 (−0.82 to −0.60) <.001
ChT, μm −20.02 (16.15) 13.63 (15.05) −33.65 (−39.49 to −27.81) <.001
UDVA −0.16 (0.36) −0.01 (0.33) −0.15 (−0.28 to −0.02) <.001

Abbreviations: AD, anterior chamber depth; AL, axial length; CCT, central corneal thickness; ChT, choroid thickness; D, diopter; IOP, intraocular pressure; K1, flat keratometry; K2, steep keratometry; LT, length thickness; SER, spherical equivalent error; UDVA, uncorrected distance visual acuity.