Extended Data Table 6.
Bivariable analysis odds ratio for the association between various factors and signing consent into a non-industry sponsored study.
Bivariable Analysis for signing consent documents | Bivariable Analysis for signing consent documents in patient’s primary language | ||||||
---|---|---|---|---|---|---|---|
Variable | OR | 95% Cl | P Value | OR | 95% Cl | P Value | |
Age | |||||||
Age at consent (per year) | 0.99 | 0.98–0.99 | <0.001 | 0.99 | 0.98 0.99 | <0.001 | |
Language | |||||||
Enqlish Primary | Reference | Reference | |||||
Primary Other than Englisha | 0.50 | 0.43–0.59 | <0.001 | 0.25 | 0.19–0.32 | <0.001 | |
Limited English Proficiencyb | 0.47 | 0.38–0.57 | <0.001 | 0.24 | 0.18–0.32 | <0.001 | |
Race and Ethnicity | |||||||
Non-Hispanic White | Reference | Reference | |||||
Asian or Pacific islander | 0.61 | 0.53–0,69 | <0.001 | 0.61 | 0.53–0.70 | <0.001 | |
Black | 1.22 | 0.92–1.36 | 0.250 | 1.13 | 0.93–1.37 | 0.215 | |
Hispanic | 0.81 | 0.71–0.92 | 0.002 | 0.79 | 0.69–0.90 | <0.001 | |
Other | 1.44 | 1.13–1,83 | 0.004 | 1.44 | 1.13–1.85 | 0.004 | |
Unknown | 3.34 | 2.89–3.94 | <0.001 | 3.36 | 2.84–3.97 | <0.001 | |
Study Type | |||||||
Interventional | Reference | Reference | |||||
Observational | 32.4 | 25.1–41.8 | <0.001 | 31.1 | 24.1–40.1 | <0.001 | |
Gender | |||||||
Male | Reference | Reference | |||||
Female | 0.37 | 0.34–0.40 | <0.001 | 0.36 | 0.33–0.39 | <0.001 | |
Histology | |||||||
Single Solid Malignancy | Reference | Reference | |||||
Healthy | 1.62 | 1.23–2.14 | <0.001 | 1.70 | 1.28–2.27 | <0.001 | |
Multiple Histology | 0.46 | 0.42–0.50 | <0.001 | 045 | 0.41–0.49 | <0.001 | |
Single Heme Maliqnancy | 0.07 | 0.05–0.09 | <0.001 | 0.07 | 005–0.09 | <0.001 |
Patients with a primary language other than English compared to patients with English as their primary language.
Patients with limited English proficiency compared to patients with English as their primary language. Odds ratios (with 95% CI) were estimated from a logistic regression model with Generalized Estimating Equations clustered by patient identifier. P-values reported are two tailed. No adjustments were made for multiple comparisons. Abbreviations, OR; odds ratio, CI; confidence Interval.