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. 2024 Apr 11;13(4):352. doi: 10.3390/antibiotics13040352

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) Volcano plot showing significantly expressed upregulated and downregulated metabolites between LAST vs. CPG. (B) Top 20 significant metabolites showing a variable importance in projection (VIP ≥ 1) score in LAST vs. CPG. (C) Top 30 KEGG pathway significantly enriched by differentially abundant metabolites between LAST vs. CPG, (p ≤ 0.05). Red color indicates the upregulated metabolic pathways, and blue color indicates the downregulated metabolic pathways, and bubble dot size shows the abundance of enrichment.