Table A2.

Methodological Quality Assessment according to Cochrane Risk of Bias Tool and Jadad Scoring [46,55].

Study	Random Sequence Generation	Allocation Concealment	Blinding Patients/Personel	Blinding Outcome Assess	Incomplete Outcome	Select Reporting	Other Bias	Overall Jadad [0–5]
Bendel, 1988 [20]	+	+	-	-	+	+	+	2	-	=High Risk
Bendel, 1989 [19]	?	+	-	-	+	+	+	1
Bräunig, 1992 [36]	?	?	?	?	+	-	+	1	+	=Low Risk
Cohen, 2004 [18]	+	+	+	+	?	+	+	4
Forth, 1981 [17]	+	-	-	?	?	-	?	1	?	=Unclear
Freyer, 1974 [22]	+	-	-	-	+	+	+	1
Goel, 2004 [38]	+	+	+	+	+	+	+	5
Grimm, 1996 [23]	+	?	+	+	+	+	+	5
Hall, 2007 [24]	+	+	+	+	?	?	+	4
Helbig, 1961 [25]	?	-	-	-	+	+	+	1
Jawad, 2012 [26]	+	+	+	+	?	?	+	5
Kolev, 2022 [27]	+	-	-	+	+	+	+	2
Berg, 1998 [21]	?	+	+	?	+	+	+	3
Melchart, 1998 [15]	+	+	-	?	+	+	+	4
Ogal, 2021 [14]	+	+	?	+	+	+	+	5
O’Neil, 2008 [28]	+	+	+	+	-	+	+	4
Osama 2020 [29]	+	+	-	-	-	+	?	1
Raus, 2015 [39]	+	+	+	+	+	+	+	5
Schmidt 1990 [30]	?	+	?	?	+	+	+	4
Schulten, 2001 [40]	+	-	+	+	+	?	+	3
Spasov, 2004 [41]	+	-	-	-	?	?	?	2
Sperber, 2004 [31]	?	?	+	+	+	+	+	3
Sumer, 2023 [37]	+	+	?	?	+	+	+	4
Taylor03-Weber05 [35,42]	+	+	+	+	+	+	+	5
Tiralongo, 2012 [32]	+	+	+	+	?	+	+	5
Turner, 2000 [33]	?	?	?	+	+	+	+	3
Turner, 2005 [16]	+	?	+	+	+	+	+	4
Yakoot, 2011 [43]	+	+	+	+	+	?	+	5
Zhang, 2003 [34]	+	+	-	-	?	+	+	3