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The NMDAR antagonist AP-5 abrogates the pressor (A) but not the bradycardic (B) response elicited by NMDA infusion (180 μg/kg/min; 9 μl/min) in conscious male Sprague-Dawley rats. NMDA or vehicle (saline) was infused for 30 min. Values are means ± S.E.M. of five observations. *, P < 0.05 versus saline (vehicle). #, P < 0.05 versus NMDA.
