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Treatment with GS-6201 (4 mg/kg) every 12 h for 14 days led to a significant reduction in plasma levels of inflammatory markers associated with AMI. Plasma concentrations of IL-6, TNF-α, soluble E-selectin (sE-selectin), soluble ICAM (sICAM), and soluble VCAM (sVCAM) were measured by using Luminex at day 28 after surgery. +, P < 0.05 versus vehicle; *, P < 0.001 versus sham.
