Table 2.
Parameter | Patients with IgA Vasculitis (Median, Interquartile Range) | Control Group (Median, Interquartile Range) (N = 33) | p * | p ** | p *** | p **** | p ***** | p ****** | ||
---|---|---|---|---|---|---|---|---|---|---|
Onset (N = 69) | Follow Up 3 Months (N = 63) | Follow Up 6 Months (N = 56) | ||||||||
S100A8/A9 (ng/mL) | 5348.00 (3171.00–8000.00) | 2115.00 (1338.00–2725.00) | 2013.00 (1196.40–4126.15) | 1132.00 (797.50–2085.30) | <0.0001 | 0.0086 | 0.0011 | <0.0001 | <0.0001 | 0.3364 |
ESR (mm/h) | 15.00 (9.00–23.00) | 6.00 (4.00–9.00) | 7.00 (5.00–10.75) | 5.00 (4.00–9.25) | <0.0001 | 0.3540 | 0.0958 | <0.0001 | <0.0001 | 0.3866 |
CRP (mg/L) | 5.50 (2.52–16.28) | 0.70 (0.30–1.78) | 0.90 (0.30–1.48) | 0.00 (0.00–0.00) | <0.0001 | 0.1474 | 0.1010 | <0.0001 | <0.0001 | 0.5718 |
WBC (×109/L) | 10.10 (8.28–12.10) | 7.30 (5.96–9.00) | 6.95 (5.75–8.02) | 5.50 (4.70–6.60) | <0.0001 | 0.0028 | 0.0045 | <0.0001 | <0.0001 | 0.1173 |
C3 (g/L) | 1.35 (1.20–1.52) | 1.16 (1.06–1.31) | 1.19 (1.06–1.29) | 1.05 (0.94–1.20) | 0.0062 | 0.1288 | 0.1784 | 0.0091 | 0.0058 | 0.7504 |
C4 (g/L) | 0.26 (0.20–0.33) | 0.21 (0.16–0.25) | 0.22 (0.16–0.26) | 0.16 (0.13–0.24) | 0.0102 | 0.1491 | 0.1532 | 0.0072 | 0.0126 | 0.9835 |
Fibrinogen (g/L) | 3.40 (2.70–3.80) | 2.60 (2.40–3.30) | 2.70 (2.30–3.05) | 2.55 (2.23–2.85) | 0.0181 | 0.3822 | 0.7725 | 0.0010 | <0.0001 | 0.2705 |
Albumin (g/L) | 38.70 (35.63–41.92) | 43.85 (40.65–45.48) | 44.20 (42.00–46.70) | 44.61 (40.65–47.10) | 0.0094 | 0.4796 | 0.6462 | <0.0001 | <0.0001 | 0.0479 |
Gamma globulin (g/L) | 9.60 (7.75–11.60) | 9.03 (7.32–10.72 | 9.30 (7.50–10.90) | 9.72 (8.24–12.02) | 0.8685 | 0.6838 | 0.3377 | 0.5991 | 0.2053 | 0.4876 |
Ferritin (ng/mL) | 64.00 (45.50–94.95) | 22.80 (13.20–40.00) | 28.00 (16.35–42.85) | 31.50 (21.00–48.00) | 0.0448 | 0.2951 | 0.0893 | <0.0001 | <0.0001 | 0.6486 |
Abbreviations: ESR—erythrocyte sedimentation rate; CRP—C-reactive protein; WBC—white blood cells. Legend: p *—comparison between values in patients at onset of disease and patients in control group; p **—comparison between values in patients three months after onset of disease and patients in control group; p ***—comparison between values in patients six months after onset of disease and patients in control group; p ****—comparison between values in patients at onset of disease and patients three months after onset of disease; p *****—comparison between values in patients at onset of disease and patients six months after onset of disease; p ******—comparison between values in patients three months after onset of disease and patients six months after onset of disease. Statistically significant values (p < 0.05) are bolded in table.