Table 1.
Demographics and disease characteristics of NF2-related schwannomatosis patient cohort.
| Patient Characteristics | Patients, n = 17 | |
|---|---|---|
| Alive, n (%) | 16 (94.1) | |
| Age, years, median (range) | Time of diagnosis Start of treatment |
39.1 (16.5–67.3) 48.1 (22.9–70.7) |
| Female, n (%) | 9 female (52.9) | |
| Family history of NF2, n (%) | 2 (11.8) | |
| Previous treatment, yes, n (%) | Total | 11 (64.7) |
| Surgical resection Target vestibular schwannoma Non-target tumor(s) |
10 (58.8) 2 (11.8) 10 (58.8) |
|
| Radiotherapy Target vestibular schwannoma Non-target tumor(s) |
3 (17.6) 0 (0.0) 3 (17.6) |
|
| NF2 classification, n (%) 1 | Class 1 Class 2 Class 3 |
15 (88.2) 0 (0.0) 2 (11.8) |
| Tumor localization, n (%) | Unilateral vestibular schwannoma Bilateral vestibular schwannoma |
2 (11.8) 15 (88.2) |
| Non-vestibular schwannoma Central nervous system Peripheral nervous system |
12 (70.6) 12 (70.6) 3 (17.6) |
|
| Total tumor count, median (range) | 12 (2–40) | |
1 According to the updated diagnostic criteria [20]. Legend: n = number of patients; NF2 = NF2-related schwannomatosis.