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Expression levels of matrix metalloproteinase 12 (MMP12) and proinflammatory cytokines in DSS-induced EGR1 KO mice. Nine-week-old C57/BL6 wild-type (WT) and Egr1 KO (Egr1−/− mice) were orally administrated with water containing 0.5% DSS for 30 days. (A) MMP-12, (B) TNF-α, (C) IL-6, and (D) IL-1 expression in colon tissue section and extracts, as determined by IHC and ELISA. Scale bars represent 20 μm in ×40 magnification. Values are the mean ± SEM.
