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IC50 values of selected synthetic compounds by COX-2 and COX-1 enzymatic assay.
| Compound | COX-2 IC50(µM) | COX-1 IC50(µM) | Selectivity Index |
|---|---|---|---|
| T2 | 12 | -- | -- |
| T3 | 0.781 | 4.655 | 5.960 |
| T5 | 0.781 | 5.596 | 7.165 |
| T6 | 1.562 | -- | -- |
| T9 | 3.5 | -- | -- |
| Celecoxib | 0.3 | -- | -- |
-- Not determined.
