Table 2.

Flavonoids and other compounds from fruits and vegetables, which can modulate MMP-2 and MMP-9 activity and/or levels.

Product	Name	Sources	MMP-2	MMP-9	Models	Refs.
	Quercetin	Vegetables, seeds, and grains	Suppression	Suppression	HSC-6 cells SCC-9 cells 2K1C rats	[91,92,93,94]
	Kaempferol	Tea, cabbage, beans, tomato, strawberries, and grapes	Suppression Suppression	Unknown Suppression	SCC-4 cells MCF-7 cells	[95,96,97]
	Naringenin	Grapefruit, bergamot, orange, tomatoes, and cocoa	Suppression	Suppression	A549 cells	[98,99]
	Luteoin	Salvia, broccoli, parsley, thyme, green pepper, and artichoke	Suppression Suppression Suppression	Suppression Suppression Suppression	Mice A2780 cells, mice	[100,101,102]
	Myricetin	Tomatoes, nuts, oranges, berries, tea, and red wine	Suppression Suppression Suppression Suppression	Unknown Suppression Suppression Suppression	COLO 205 cells MDA-Mb-231 cells A549 cells	[103,104,105,106]
	Baicalein	Root of Scutellaria Baicalensis	Suppression Suppression Suppression Suppression	Unknown Unknown Suppression Suppression	SK-MEL-28 BON1 cells CRL-1427 cells A375 cells, mice	[107,108,109,110,111]
	Genistein	Food, soya products	Unknown	Suppression	Mice	[112]
	Silibinin	Fruits	Unknown	Suppression	Mice	[113,114,115]
	Ginsenoside	Panax root	Suppression	Suppression	3T3-L1 cells	[116,117,118,119,120,121,122]
	Amenoflavone	Selaginella tamariscina	Suppression	Suppression	Breast cancer cells B16F-10 cells	[123,124,125,126]
	Sulforaphane	Cabbage and broccoli	Unknown	Suppression	Abdominal cancer cells	[127,128,129,130]
	Caffeic acid	Fruits, vegetables, wine, olive oil, and coffee	Unknown	Suppression	Colon cancer cells	[131,132,133,134]
	Combretastatin A-4	Willow tree	Suppression	Suppression	A549 cells	[135,136,137,138,139,140]
	Pterostilbene	Blueberries and grape	Suppression	Unknown	A7r5 cells	[141,142,143,144,145,146,147]
	Decursin	Angelica gigas	Unknown	Suppression	Breast cancer cells	[148,149,150,151,152,153]