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ATP binds nucleic-acid-binding pockets of folded domains beyond RRM. (a) ATP complex of the acidic domain (AcD) of Syncrip. (b) ATP complexes of N-terminal domain (NTD) and C-terminal domain (CTD) of SARS-CoV-2 nucleocapsid protein, both of which are bound with hydroxychloroquine (HCQ). CTD is a homo-dimer with two monomers colored in blue and purple, respectively.
