ALI |
Acute lung injury |
AMs |
Alveolar macrophages |
AP-1 |
Activator protein-1 |
ARDS |
Acute respiratory distress syndrome |
ATII |
Alveolar cell type II |
BAL |
Bronchoalveolar lavage |
cAMP |
Cyclic adenosine monophosphate |
CAP |
Community-acquired pneumonia |
cGMP |
Cyclic guanosine monophosphate |
CREB |
cAMP response element-binding protein |
CRP |
C-reactive protein |
DAMPs |
Damage-associated molecular pattern molecules |
ERK |
Extracellular signal-regulated kinases |
FQs |
Fluoroquinolones |
GM-CSF |
Granulocyte–macrophage colony-stimulating factor |
hPBL |
Human peripheral blood lymphocytes |
IFN |
Interferon |
IL |
Interleukin |
iNOS |
Inducible NO synthase |
IκB |
Inhibitory κappa B |
JNK |
c-Jun N-terminal kinases |
KC |
Keratinocytes-derived chemokine |
LPS |
Lipopolysaccharide |
MAMPs |
Microbe-associated molecular patterns |
MAPK |
Mitogen-activated protein kinase |
MCP-1 |
Monocyte chemotactic protein |
MIP-1α |
Macrophage inflammatory protein 1α |
Mpro
|
Main protease |
NET |
Neutrophil extracellular trap |
NF-κB |
Nuclear factor κappa-B |
NO |
Nitric oxide |
PAMPs |
Pathogen-associated molecular patterns |
PBMCs |
Peripheral blood mononuclear cells |
PDEs |
Phosphodiesterases |
PKA |
Protein kinase A |
PRRs |
Pattern recognition receptors |
RBCs |
Red blood cells |
RCT |
Randomised controlled trial |
ROS |
Reactive oxygen species |
SARS-CoV-2 |
Severe acute respiratory syndrome coronavirus 2 |
TAK1 |
Transforming growth factor-activated kinase 1 |
TLR |
Toll-like receptor |
TNF |
Tumour necrosis factor |