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Gene structure of TEK and identified primary congenital glaucoma (PCG) variants. The TEK gene consists of 23 exons and codes a protein of 1124 amino acids, featuring Ig-like (Ig), EGF-like (EGF), fibronectin type III (FN III), and protein kinase (Kinase) domains. Variants reported in PCG patients are depicted, excluding those located in intronic regions: c.1624+5G>A, c.760+2T>C, and c.3300+2delT. Asterisk (*): premature stop codon.
