Table 2.
Comparison of familial and birth parameters between groups.
| Characteristics | TD (N = 774,778) | ASD (N = 1163) | Statistics |
|---|---|---|---|
| Mother’s age c Mean (SD, Min–Max) | 30.02 (5.71, 15–55) | 31.43 (5.65, 19–52) | t (767,831) = −8.27 ***, d = 0.24 |
| Missing | 8688 (1.12%) | 2 (0.17%) | |
| Birth weight (Kg) Mean (SD, Min–Max) | 3.21 (0.51, 0.4–6) | 3.15 (0.58, 0.72–4.77) | t (747,034) = 3.96 ***, d = 0.1 |
| Missing | 28,871 (3.72%) | 34 (2.92%) | |
| Pregnancy week c Mean (SD, Min–Max) |
39.09 (1.8, 23–43) | 38.65 (2.07, 25.2–42.3) | U = 437,787,198 ***, d = 0.004 |
| Missing | 29,465 (3.8%) | 32 (2.75%) | |
| Males c N (%) | 398,069 (51.4%) | 911 (78.3%) | ***, φ = 0.021 |
| Preterm births (pregnancy week < 37) | 54,937 (7.1%) | 132 (11.3%) | ***, φ = 0.006 |
| Missing | 41,496 (5.4%) | 52 (4.5%) | |
| Birth type | χ2(2) = 86.04 ***, φc = 0.011 | ||
| Spontaneous | 539,004 (69.6%) a | 693 (59.6%) b | |
| Cesarean | 129,685 (16.7%) a | 309 (26.6%) b | |
| Instrumental | 37,232 (4.8%) a | 71 (6.1%) b | |
| Missing | 68,857 (8.9%) | 90 (7.7%) | |
| Multiple Pregnancy | χ2(3) = 18.87 ***, φc = 0.005 | ||
| Single | 741,871 (95.8%) a | 1084 (93.2%) b | |
| Twin | 31,783 (4.1%) a | 76 (6.5%) a | |
| Triplet | 1058 (0.1%) a | 3 (0.3%) a | |
| Other | 66 (0.001%) a | 0 (0%) a |
Note. Continuous variables were compared using independent samples t-test, while nominal variables with Chi square or Fisher exact tests. Missing data were not included in the comparisons. ASD: Autism spectrum disorder. TD: Typical development. a,b Groups with different subscripts are significantly different based on pairwise adjusted Z-tests. c These features were among the top important features in the final model. *** p < 0.001.