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Mechanical index vs. fold change in biomarker level for animals receiving FUS-BBBO vs. controls, or the change from pre- to post-FUS-BBBO [24,30,31,32,34]. Abbreviations: cfDNA = circulating free DNA; bp = base pair; EGFRvIII = epidermal growth factor receptor variant III; TERT C228T = telomerase reverse transcriptase promotor mutation C228T; mRNA = messenger RNA; eGFP = enhanced green fluorescent protein; GFAP = glial fibrillary acidic protein.
