FDA	Food and Drug Administration
UAE	Ultrasound-assisted extraction
RSM	Response Surface Methodology
HPLC	High-performance liquid chromatography
LC-MS	Liquid chromatography tandem mass spectrometry
DES	Deep eutectic solvent
AFO	Algar–Flynn–Oyamada method
BKVK	Baker–Venkataraman method
PTZ	Pentylenetetrazol
NRG	Neuregulin
CDK	Cyclin-dependent kinase
IC50	Half maximal inhibitory concentration
COX-2	Cyclooxygenase-2
ITS	Internal Transcribed Spacer
CHS	Chalcone synthase
FNS	Flavonol synthase
CHI	Chalcone isomerase
IFS	Isoflavone synthase
F3′H	Flavonoid 3′-hydroxylase
PAL	Phenylalanine ammonia-lyase
TAL	Tyrosine ammonia-lyase
C4H	Cinnamic acid-4-hydroxylase
4CL	4-coumaroyl-CoA
PEP	Precursors 2-(phenoloxy) prop-2-en-1-olate
E4P	(S)-2-hydroxy-4-oxobutyl dihydrogen phosphate
TcCGT	Trollius chinensis C-glycosyltransferase
GmSUS	Glycine max sucrose synthase
DPPH	2-diphcnyl-l-picrylhydrazyl
ABTS	2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)
ROS	Reactive oxygen species
EE	Ethanolic extract
FG	Flavonoid glycosides
NF-κB	Nuclear factor-kappa B
5-HT	5-hydroxytryptamine
PGE2	Prostaglandin E2
HO-1	Heme oxygenase 1
Nrf2	Nuclear factor erythroid 2-related factor 2
LTB4	Leukotrienes B4
TNF-α	Tumor necrosis factor-alpha
IL-6	Interleukin-6
IL-8	Interleukin-8
TLR4	Toll-like receptors 4
Akt	Protein kinase B
NQO1	NAD(P)H: quinone oxidoreductase 1
MyD88	Myeloid differentiation primary response 88
p38MAPK	Phospho-p38 mitogen-activated protein kinases
JNK	c-Jun N-terminal kinase; 6-MeOF, 6-methoxyflavone
LDH	Lactate dehydrogenase
CK-MB	Creatine kinase muscle/brain
CABG	Coronary artery bypass grafting
CVD	Cardiovascular disease
PEPCK	Phosphoenolpyruvate carboxykinase
G-6-Pase	Glucose-6-phosphatase
ACC	Acetyl coenzyme A carboxylesterase
IRS-2	Insulin receptor substrate-2
GLUT4	Glucose transporter protein 4
IR	Insulin-resistant
PI3K	Phosphatidylinositol 3-kinase
IRS-1	Insulin receptor substrate-1
GSK-3β	Phosphoglycogen synthase kinase
AGEs	advanced glycosylation end products
NMR	Nuclear magnetic resonance spectroscopy
MIC	Minimum inhibitory concentration
TC	Total cholesterol
TG	Triacylglycerol
TBIL	total bilirubin
NAFLD	Non-alcoholic fatty liver disease
A2Ar	Adenosine A2a receptor
ERK	Extracellular regulated protein kinases
MMP-2	Matrix Metallopeptidase 2
TGF-β1	Tubuloglomerular feedback β1
BLM	Bleomycin
LC3	Microtubule-associated protein1 light chain 3
PINK1	PTEN-induced putative kinase 1
LAMP1	Lysosome-associated membrane proteins 1
TFEB	Transcription factor EB
EMT	Epithelial–mesenchymal transition
SAPK	Stress-activated protein kinase
STAT-1	Signal transducer and activator of transcription 1
SAPK	Stress-activated protein kinase; mTOR, mammalian target of rapamycin
VEGF	Vascular endothelial growth factor
Bcl-2	B-cell lymphoma-2
Bax	BCL2-associated X
PLK1	Polo-like kinase
PPARγ	Peroxisome proliferator-activated receptors γ
TFH	Hippophae rhamnoides
PRKCA	Protein kinase C alpha
IGF-1	Insulin-like growth factor-1
UCP2	uncoupling protein 2
GLP-1R	Glucagon-like peptide-1 receptor
EGCG	Epigallocatechin gallate
TBARS	Thiobarbituric acid reactive substances
FAS	fatty acid synthase; KGM, Konjac glucomannan
GPx	Glutathione peroxidase
TSA	Thiolated sodium alginate
GPx	Glutathione peroxidase
PVA	Polyvinyl alcohol
SA	Sodium alginate
ALOX5	Arachidonic acid-5-lipoxygenase
MMP	Matrix metalloproteinases
LNQ-MF	Luteolin, Naringenin and Quercetin-loaded Micellar Formulation
T2DM	diabetes mellitus type 2
Sirt3	recombinant Sirtuin 3
YAP1	Yes-associated protein 1
HMC	Hesperidin methyl chalcone