Figure 3.

Each miRNA-based subgroup had distinctive plasma proteins. (A) Heatmap shows the levels of all the 387 proteins. (B) Distinctive proteins in each subgroup (red frames) were extracted as differentially expressed proteins between one subgroup and other subgroups (two-tailed unpaired t-test, Benjamini–Hochberg corrected p < 0.1). ‘1-down’ is the downregulated proteins in subgroup 1. ‘1-up’ is the upregulated proteins in subgroup 1. ‘2-up’ is the upregulated proteins in subgroup 2. ‘3-down’ is the downregulated proteins in subgroup 3. (C) Box-and-swarm plots show expression levels of a representative protein in each subgroup.