Table 3.
PPARγ, ADIPOQ, ADIPOR1, ADIPOR2 gene polymorphisms distribution in ADPKD population.
| Gene | SNP (rs Number) | n Patients | Het/Homo | Age | Adiponectin (µg/mL) (st.dev) |
eGFR (mL/min/1.73 mq) (st.dev) |
Systolic Blood Pressure (mm/Hg) (st.dev) |
Diastolic Blood Pressure (mm/Hg) (st.dev) |
|---|---|---|---|---|---|---|---|---|
| PPARγ | c.34 C>G (rs1801282) | 14 | 14/0 | 46 (15.35) | 15.92 (3.27) | 65.21 (36.87) | 133.30 (22.65) | 83.52 (18.18) |
| ADIPOQ | c.45C>T (rs2241766) | 26 | 20/6 | 43 (14.84) | 14.11 (4.39) | 66.18 (31.85) | 136.09 18.17) | 82.97 (9.49) |
| c.268G>A (rs62625753) | 4 | 4/0 | 58 (18.6) | 14.25 (5.00) | 50.25 (37.73) | 136.67 (5.77) | 88.33 (7.63) | |
| c.214+62G>T (rs1501299) | 29 | 24/5 | 43.7(16.28) | 14.5 (4.42) | 78.3 (35.15) | 134.0 (18.11) | 84.4 (10.21) | |
| ADIPOR1 | c. 94-8T>G (rs2275737) | 23 | 17/6 | 44 (12.92) | 13.25 (3.86) | 64.34 (31.36) | 134.14 (13.36) | 82.14 (8.16) |
| c. 94-12>G (rs2275738) | 25 | 18/7 | 44 (12.92) | 13.25 (3.86) | 64.34 (31.36) | 134.14 (13.36) | 82.14 (8.16) | |
| ADIPOR2 | c.795G>A (rs16928751) | 18 | 16/2 | 44 (13.60) | 14.11 (3.97) | 67.80 (38.35) | 133.53 (13.89) | 84.12 (10.64) |
| c.1718C>T (rs1044471) | 23 | 17/6 | 41 (12.65) | 12.98 (3.56) | 68.99 (33.83) | 132.32 (13.50) | 80.89 (8.39) | |
| c.1642C>T (rs12342) | 16 | 13/3 | 45 (14.47) | 14.57 (4.39) | 68.86 (34.50) | 134.25 (15.83) | 82.97 (9.53) |