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Schematization of clinical staging in age-related macular degeneration (AMD). (A) No signs of AMD with normal outer retina and choroid. (B) Early AMD is characterized by the presence of drusen ranging between 63 μm and 125 μm without pigmentary changes. (C) Intermediate AMD is represented by large drusen > 125 μm and/or pigmentary abnormalities. (D) Late AMD with neovascularization arising from choroidal circulation.
