Figure 6.

HK-VDAC interaction is decreased in sural nerve of CMT4G patient. Representative Western blots showing HK1 and VDAC protein amount in sural nerve extracts (loading control) from control patient (control) and CMT4G patient (CMT4G) and in immunoprecipitates with control rabbit immunoglobulins (IP Cont IgG) or with rabbit immunoglobulin directed against HK (IP HK IgG). VDAC Western blot shows that less VDAC coimmunoprecipitates with HK in sural nerve extracts of CMT4G patients. n = 1 patient and 1 control.