Table 2.
The main features of the procedure, in-hospital complications, and 3-month outcomes.
| Variable | Total (N = 300) |
DT (N = 187) |
NH (N = 55) |
DH (N = 58) |
p |
|---|---|---|---|---|---|
| Procedure | |||||
| IVT, n (%) | 176 (58.7) | 111 (59.4) | 28 (50.9) | 37 (63.8) | 0.43 |
| Onset-to-needle time, median (IQR), min | 120 (168) | 120 (75) | 120 (74) | 130 (64) | 0.32 |
| Door-to-needle time, median (IQR), min | 48 (35) | 43 (27) | 43 (27) | 60 (48) | <0.001 |
| Onset-to-groin time, median (IQR), min | 250 (234) | 204 (197) | 204 (196) | 328 (151) | <0.001 |
| Door-to-groin time, median (IQR), min | 87 (50) | 95 (45) | 95 (41) | 64 (65) | <0.001 |
| MT duration, median (IQR), min | 32 (40) | 34 (45) | 35 (46) | 30 (36) | 0.77 |
| Passes in MT ≤ 3, n (%) | 170 (56.7) | 99 (52.9) | 37 (67.3) | 34 (58.6) | 0.05 |
| Stent implantation, n (%) | 45 (15) | 30 (16) | 9 (16.4) | 6 (10.3) | 0.59 |
| TICI 2b-3, n (%) | 226 (75.3) | 144 (77) | 37 (67.3) | 45 (77.6) | 0.82 |
| TICI 0, n (%) | 14 (4.7) | 9 (4.8) | 2 (3.6) | 3 (5.2) | 0.62 |
| In-hospital complications | |||||
| Hemorrhagic transformation *, n (%) | 49 (16.3) | 23 (12.3) | 13 (23.6) | 13 (22.4) | 0.04 |
| Brain edema with midline deviation, n (%) | 67 (22.3) | 39 (20.9) | 14 (25.5) | 14 (24.1) | 0.63 |
| Craniectomy, n (%) | 8 (2.7) | 4 (2.1) | 2 (3.6) | 2 (3.4) | 0.74 |
| Renal insufficiency, n (%) | 37 (12.3) | 29 (15.5) | 5 (9.1) | 6 (10.3) | 0.39 |
| Renal failure, n (%) | 40 (12.3) | 29 (15.5) | 5 (9.1) | 6 (10.3) | 0.39 |
| Lower respiratory tract infection, n (%) | 68 (22.7) | 40 (21.4) | 15 (27.3) | 13 (22.4) | 0.52 |
| Urinary tract infection, n (%) | 26 (8.7) | 13 (6.9) | 7 (12.7) | 6 (10.3) | 0.3 |
| Outcomes | |||||
| Early neurological improvement **, n (%) | 39 (13) | 25 (13.6) | 11 (20) | 3 (5.2) | 0.06 |
| Excellent outcome (mRS score = 0–1), n (%) | 72 (24) | 54 (28.9) | 10 (18.2) | 8 (13.8) | 0.07 |
| Favorable outcome (mRS score = 0–2), n (%) | 106 (35.3) | 78 (41.7) | 15 (27.3) | 13 (22.4) | 0.03 |
| Death, n (%) | 63 (21) | 39 (20.9) | 10 (18.2) | 14 (24.1) | 0.71 |
* Parenchymal hematoma type 1 (PH1) or type 2 (PH2) according to the ECASS classification. ** Improvement in the NIHSS score of 4 or more points after MT. IVT, intravenous thrombolysis; IQR, interquartile range; DT, direct transfer; NH, nearby hospital; DH, distant hospital; MT, mechanical thrombectomy; TICI, thrombolysis in cerebral infarction scale score; NIHSS, National Institutes of Health Stroke Scale; mRS, modified Rankin scale.