Figure 1.

Illustrates the structural differences between younger and aging skin. In young human skin dermis, collagen fibrils are intact and normal in size (left) in contrast with reduced collagen fibrils in aged human skin dermis which leads to a reduction in cell size (right). The aging skin on the right shows a reduction and fragmentation of collagen fibers, broken elastic fibers, and diminished Hyaluronic Acid (red dots), leading to thinner fat layers and an overall loss of structural integrity and elasticity.