Table 1.
Characteristics of index patients.
| Overall | Mutation | No Mutation | |
|---|---|---|---|
| Number | 180 | 164 | 16 |
| Age (years) | 10.2 ± 4.6 | 10.1 ± 4.7 | 11.0 ± 3.3 |
| Sex (male/female) | 90/90 | 84/80 | 6/10 |
| Total cholesterol (mg/dL) | 290.5 ± 49.7 | 291.6 ± 51.1 | 279.0 ± 30.1 |
| LDL cholesterol (mg/dL) | 218.7 ± 45.6 | 220.1 ± 46.5 | 203.6 ± 33.3 |
| HDL cholesterol (mg/dL) | 56.8 ± 12.5 | 56.5 ± 12.2 | 59.6 ± 15.5 |
| Triglycerides (mg/dL) | 75.9 ± 30.6 | 75.6 ± 31.3 | 78.6 ± 23.0 |
| CHD in I-II-degree relatives (number, %) | 140/180 (77.8%) | 126/164 (76.8%) | 15/16 (87.5%) |
| pCHD in I-II-degree relatives (number, %) | 92/180 (51.1%) | 83/164 (50.6%) | 9/16 (56.2%) |
| pCHD in parents, n % | 26/180 (14.4%) | 22/164 (13.4%) | 3/16 (18.7%) |