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. 2024 Apr 10;22(4):168. doi: 10.3390/md22040168

Table 2.

Physiological effects of seaweed compounds investigated for the treatment of diabetic diseases.

Detected Activity Seaweed Compound Physiological Effects of
Seaweed Compounds
References
Anti-inflammatory properties Polysaccharides
Polyphenols
Reduced inflammatory effect in chronic inflammation associated with insulin resistance [7,70,71,72]
Antioxidant properties Polysaccharides Antioxidants protect against the development of diabetic complications [60,73]
Change in lipid metabolism Polysaccharides
Polyphenols
Reduced levels of triglycerides and LDL-C [60,62,74,75,76]
α-glucosidase inhibition Polysaccharides
Polyphenols
Peptides
Slowed down the absorption of glucose, reducing the peak glucose levels in blood [7,10,70,77,78,79,80,81,82,83]
α-amylase inhibition Polysaccharides Slower digestion and absorption of carbohydrates to promote better glycemic control [8,84]
DPP-4 inhibition Polysaccharides
Peptides
Inhibition of DPP-4, which inactivates hormones involved in insulin secretion [85,86,87,88,89,90]