Table 2.
Demographic and clinical features of ALK mutant NSCLC patients according to PNI level and mGPS
| Parameters | PNI | mGPS | |||||
|---|---|---|---|---|---|---|---|
| < 50 | ≥ 50 | P | 0 | 1 | 2 | P | |
| Age (Median, min–max) | 52 (31–76) | 49 (26 – 70) | 0.387 | 52.5 (35–74) | 52 (26–76) | 40 (31–58) | 0.087 |
| Sex (M/F) (%) | 65.5/35.5 | 42.9/57.1 | 0.11 | 45/55 | 68.2/31.8 | 50/50 | 0.29 |
| Smoking (%) | 0.43 | 0.49 | |||||
| Active | 4.3 | 5.6 | 15 | 10.5 | 12.5 | ||
| Former | 34.8 | 16.7 | 20 | 21.1 | 37.5 | ||
| Non-smoker | 60.9 | 77.8 | 65 | 68.4 | 50 | ||
| ECOG PS (%) | 0.23 | 0.68 | |||||
| 0 | 7.8 | 6.1 | 2.2 | 4.5 | 1.4 | ||
| 1 | 60.2 | 55.9 | 65.4 | 62.8 | 59.7 | ||
| 2 | 30.9 | 35.6 | 29.8 | 30.5 | 36.4 | ||
| 3 | 1.1 | 2.4 | 3.6 | 2.2 | 2.5 | ||
| Brain Met. (Y/N- %) | 32/68 | 40/60 | 0.57 | 38.9/61.1 | 31.6/68.4 | 37.5/67.5 | 0.89 |
| Liver Met. (Y/N- %) | 17.9/82.1 | 9.5/90.5 | 0.409 | 10.5/89.5 | 18.2/81.8 | 12.5/87.5 | 0.77 |
| Adrenal Gland Met. (Y/N- %) | 55.2/44.8 | 28.6/71.4 | 0.061 | 40/60 | 50/50 | 37.5/62.5 | 0.74 |
| Lung Met. (Y/N- %) | 20.7/79.3 | 19/81 | 0.88 | 10/90 | 31.8/68.2 | 12.5/87.5 | 0.17 |
| Pleural Met. (Y/N- %) | 27.6/72.4 | 28.6/71.4 | 0.93 | 35/65 | 22.7/77.3 | 25/75 | 0.66 |
| Bone Met. (Y/N- %) | 37.9/62.1 | 33.3/66.7 | 0.73 | 35/65 | 27.3/72.7 | 62.5/37.5 | 0.202 |
M male, F Female, Met metastasis, ECOG PS Eastern Cooperative Oncology Group Performance score, Y yes, N no, mGPS modified Glasgow prognostic score, PNI Prognostic nutritional index