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. 2024 Apr 16;10(8):e29298. doi: 10.1016/j.heliyon.2024.e29298

Table 1.

Results of the meta-analysis of the effects of accommodation on geometrical parameters of the crystalline lens in humans.

Group Subgroup (apparatus) Studies (n) Heterogeneity test
Effect model Results of meta-analysis
I2 (%) P value MD (95% CI) P value
LT 18 96.60 0.000 Random 0.04 (0.03, 0.06) <0.001
OCT and IOL Master 12 86.30 0.000 Random 0.04 (0.02, 0.05) <0.001
MRI 5 88.10 0.000 Random 0.06 (0.04, 0.08) <0.001
A-scan ultrasonography 1 0.00 N/A Random 0.05 (0.05, 0.05) <0.001
LD 6 50.10 0.075 Random −0.06 (−0.07, −0.05) <0.001
MRI 4 12.10 0.332 Random −0.07 (−0.08, −0.05) <0.001
A-scan ultrasonography 1 0.00 N/A Random −0.05 (−0.06, −0.04) <0.001
OCT 1 0.00 N/A Random −0.08 (−0.12, −0.05) <0.001
ACR 8 96.50 0.000 Random −0.53 (−0.64, −0.41) <0.001
OCT and IOL Master 7 96.70 0.000 Random −0.58 (−0.71, −0.45) <0.001
MRI 1 0.00 N/A Random −0.25 (−0.31, −0.19) <0.001
PCR 9 94.70 0.000 Random −0.14 (−0.19, −0.09) <0.001
OCT and IOL Master 7 95.80 0.000 Random −0.16 (−0.23, −0.08) <0.001
MRI 2 0.00 0.648 Random −0.09 (−0.12, −0.07) <0.001
LCP 3 0.00 1.000 Fixed −0.01 (-0.02, −0.00) <0.001
TCSA 2 97.00 0.000 Random 0.58 (−0.41, 1.57) >0.05

ACR, anterior curvature radius; LCP, lens center position; LD, lens diameter; LT, lens thickness; MRI, magnetic resonance imaging; N/A, not available; OCT, optical coherence tomography; PCR, posterior curvature radius; TCSA, total cross-sectional area.