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Amino acid substitutions in Nsp12 observed at baseline (compared with Wuhan-Hu-1 reference sequence).
| Number of Participants with Amino Acid Substitutions Occurring in ≥2 Participants at Baseline, n (%) a | ||
|---|---|---|
| Severe COVID-19 Study | Moderate COVID-19 Study | |
| P323L | 50/53 (94%) | 8/9 (88%) |
| A554V | 2/64 (3.1%) | 0/13 (0%) |
a The denominator is based on the number of participants with sequence coverage at the site of the substitution.
