Abbreviation	Definition
AD	Alzheimer’s disease
BBR	Berberine
BSC	Bristol Stool Chart
BDNF	Brain-derived Neurotrophic Factor
CUR	Curcumin
CRF	Case Report Form
CI	Confidence Interval
COX-2	Cyclooxygenase-2
cAMP	Cyclic Adenosine Monophosphate
FODMAP	Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols
FDA	Food and Drug Administration
GI	Gastrointestinal
GP	General Practitioner
GCP	Good Clinical Practice
GRAS	Generally Recognized As Safe
5-HT	5-Hydroxytryptamine
IBS	Irritable Bowel Syndrome
IBSSI	Irritable Bowel Syndrome Severity Index
IRB	Institutional Review Board
INF-γ	Interferon-gamma
IL-7	Interleukin-7
iNOS	Inducible Nitric Oxide Synthase
IQR	Interquartile Range
5-LOX	5-Lipoxygenase
N	Numbers
NF-kB	Nuclear Factor-kappa B
NAFLD	Non-alcoholic Fatty Liver Disease
OR	Odd Ratio
pCREB	Phosphorylated cAMP Response Element-binding
QoL	Quality of life
RCT	Randomized Clinical Trial
SAS	Statistical Analysis System
SD	Standard Deviation
TrkB	Tropomyosin Receptor Kinase B
VAS	Visual Analogue Scale
ZO-1	Zonula Occludens-1