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. 2024 Apr 19;17(4):530. doi: 10.3390/ph17040530

Figure 1.

Figure 1

Effect of the CB2 receptor agonist JWH-133 and Cannabixir® Medium Flos on weight gain. Throughout the 12-week treatment period, the body weight of all animals in each group was measured weekly. The groups were designated as follows: ConG: control group; JG: JWH-133 group; JDG: JWH-133 + donepezil group; PG: Cannabixir® Medium Flos group; PDG: Cannabixir® Medium Flos + donepezil group; WT: vehicle group. The substances were administered via gavage at a volume of 0.5 mL/100 g of body weight as follows: JWH-133 at a dose of 0.2 mg/kg, Cannabixir® Medium Flos at a dose of 2.5 mg/kg, donepezil at a dosage of 0.65 mg/kg, and a 0.1% aqueous suspension of CMC-Na used as a vehicle.