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. 2024 Apr 14;16(8):1169. doi: 10.3390/nu16081169

Figure 1.

Figure 1

Effect of silymarin and polyherbal extract on the pathological and biochemical indexes of NAFLD in mice. (a) Experiment design of silymarin and polyherbal extract intervention. (b,c) Levels of serum ALT (b) and the ratio of serum AST to ALT (c). (d) Representative morphology (Scale bars, 1 cm), representative microphotograph of hematoxylin and eosin (H&E) staining (Scale bars, 200 µm) and Oil Red O (ORO) staining (Scale bars, 100 µm) of livers. (e,f) Levels of liver TG (e) and liver TC (f); n = 7. (g–j) Levels of serum TC (g), LDL-C (h), HDL-C (i) and fasting blood glucose (j); n = 6 for the NC, MSL and PD group and n = 7 for the HF and HSL group. (k,l) Blood glucose level and area under the curve (AUC) during IGTT (k) and IPITT (l); n = 8. Values were shown as mean ± SD. Statistical significance was evaluated by two-sided one-way ANOVA with Dunnett’s post hoc test (compared with HF group); * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. ALT alanine transaminase, AST aspartate aminotransferase, TG triglycerides, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, IGTT intraperitoneal glucose tolerance test, IPITT intraperitoneal insulin tolerance test.