Figure 5.

RNA-Seq expression profiles of selected lincRNAs measured in control assays at different S. mansoni life-cycle stages. The expression levels of the ten selected lincRNAs are shown, namely: (a) SmLINC101519-IBu, (b) SmLINC105115-IBu, (c) SmLINC110492-IBu, (d) SmLINC121232-IBu, (e) SmLINC133371-IBu, (f) SmLINC142502-IBu, (g) SmLINC159037-IBu, (h) SmLINC161393-IBu, (i) SmLINC163938-IBu, and (j) SmLINC172840-IBu. These S. mansoni lincRNAs were selected after re-analysis of RNA-Seq public datasets of parasites collected from mice treated with PZQ in the “time-course experiment” [11]. The y-axis shows the expression level (shown as TMM—trimmed mean of M values) for each lincRNA in control RNA-Seq assays, as compiled by Silveira et al. [31], at the stage indicated in the x-axis as follows: miracidia/sporocysts (M/S), cercariae (C), schistosomula (S), adult males (M), and adult females (F).