Table 1.
Demographics and clinical data of the sample (n = 24). Abbreviations: M: male; NPS: new/novel psychoactive substance.
Sex, M | 19 (79.2) |
Age, years | 29.4 ± 7.5 (19–46) |
Substance abused | |
Alcohol | 9 (37.5) |
Cocaine | 11 (45.8) |
Cannabis | 11 (45.8) |
Methamphetamine | 1 (4.2) |
Ketamine | 1 (4.2) |
NPS | 1 (4.2) |
Polysubstance users | 10 (41.7) |
Diagnosis | |
Substance-induced psychosis | 18 (75) |
Schizoaffective disorder | 6 (25) |
Coexisting diagnosis | |
Personality disorders: - Personality disorder NAS - Schizoid personality disorder - Schizotypal personality disorder |
4 (16.7) 2 (8.3) 1 (4.2) 1 (4.2) |
Brexpiprazole dosage (mg) | 2.3 ± 0.9 (1–4) |
Psychotropics other than brexpiprazole | |
Antipsychotics | Olanzapine 15–20 mg/day, 2 (8.3) Promazine 40–100 mg/day, 2 (8.3) Quetiapine 100 mg/day, 1 (4.2) |
Antidepressants | Trazodone 50–220 mg, 3 (12.5) Sertraline 50 mg, 2 (8.3) Paroxetine 20 mg, 1 (4.2) Vortioxetine 10 mg, 1 (4.2) |
Mood stabilizers | Valproate 600–1500 mg/day, 6 (25) Lamotrigine 300 mg/day, 1 (4.2) Gabapentin 900–1600 mg/day, 4 (16.7) Pregabalin 150–450 mg/day, 2 (8.3) Lithium sulfate 83 mg/day, 1 (4.2) Lithium carbonate 600 mg/day, 1 (4.2) |
Benzodiazepines and Z-drugs | Lorazepam 7.5 mg/day, 1 (4.2) Clonazepam 2.5 mg/day, 1 (4.2) Delorazepam 3–10 mg/day, 3 (12.5) Diazepam 7–22 mg/day, 3 (12.5) Zolpidem 10 mg/day, 1 (4.2) |
Others | Methadone 55 mg/day, 1 (4.2) Baclofen 35 mg/day, 1 (4.2) |
Data are presented as n (%), means ± SDs, and ranges, as appropriate.