Table 4.
Different combinations of genotypes detected in control and patient populations.
| Thr16Met rs10156191 |
His664Asp rs1049793 |
Promoter Region rs2052129 |
Control Group (n = 100) |
Population Frequency (95% Cl) |
Patients Group (n = 100) |
Population Frequency (95% Cl) |
p- Value * |
|---|---|---|---|---|---|---|---|
| CC | CC | GG | 28 | 28 (19.2–36.8) | 21 | 21 (13.02–28.9) | 0.324 |
| CC | CC | GT | 12 | 11 (4.87–17.1) | 7 | 7 (2–12) | 0.335 |
| CC | CG | GG | 16 | 16 (8.81–23.2) | 18 | 18 (10.47–25.5) | 0.851 |
| CC | GG | GG | 1 | 1 (0–2.95) | 2 | 2 (0–4.7) | 1 |
| CC | CG | GT | 3 | 3 (0–6.3) | 0 | 0 | 0.324 |
| CT | CC | GG | 2 | 2 (0–4.7) | 0 | 0 | 0.497 |
| CT | CC | GT | 7 | 7 (2–12) | 5 | 5 (0.73–9.3) | 0.767 |
| CT | CG | GG | 2 | 2 (0–4.7) | 7 | 7 (2–12) | 0.170 |
| CT | CG | GT | 22 | 22 (6.41–19.6) | 17 | 17 (1.35–10.65) | 0.476 |
| CT | GG | GG | 3 | 3 (0–6.3) | 1 | 1 (0–2.95) | 0.621 |
| TT | CC | GT | 1 | 1 (0–2.95) | 1 | 1 (0–2.95) | 1 |
| TT | CG | GT | 2 | 2 (0–4.7) | 1 | 1 (0–2.95) | 1 |
| TT | GG | GG | 1 | 1 (0–2.95) | 0 | 0 | 1 |
| CT | CC | TT | 0 | 0 | 4 | 4 (0.16–7.8) | 0.121 |
| CT | CG | TT | 0 | 0 | 5 | 5 (0.16–7.8) | 0.059 |
| CT | GG | GT | 0 | 0 | 1 | 1 (0–2.95) | 1 |
| TT | CC | TT | 0 | 0 | 3 | 3 (0–6.34) | 0.246 |
| TT | CG | TT | 0 | 0 | 7 | 7 (0–2.95) | 0.014 |
* p-Value of the comparison of the different combinations of genotypes between the patient and control groups according to Fisher’s Exact Test.