Figure 6.

Serum Neutralising Antibody Responses Following Immunisation with Recombinant VP2 or Different Doses of Double-Shelled VLPs. (A) Plaque reduction serum antibody titres against BTV10 following immunisation with recombinant VP2 alone or doubled-shelled VLPs, demonstrating the difference in 50% titres. (Adapted from [7]) (B) Average serum neutralising antibody titres from sheep (n = 4) immunised with two doses of VLPs at 10, 50, 100 or 200 µg. At day 117, sheep were challenged with virulent BTV. No signs of BT disease or viremia were detected in any of the VLP-immunised animals (Adapted from [29]).