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. 2024 Apr 9;16(8):1100. doi: 10.3390/nu16081100

Figure 3.

Figure 3

Faecalibacterium prausnitzii colonization inhibited the expression of inflammatory cytokines in sleep-deprived mice. (A) Representative captures of immunohistochemical of F4/80 in colon, Bar = 100 μm. (B) The quantification of F4/80+ cells (n = 6). (C,D) The levels of cytokines (TNF-α and IL-6) in the colon (n = 6). (E) The levels of LPS in the colon (n = 6). (F–K) The mRNA levels of Tnf-α, Il-6, Il-1β, F4/80, Mcp-1 and Il-10 in the colon (n = 6). One-way ANOVA was utilized to evaluate variances. The study included a control group (CON), a group colonized with Faecalibacterium prausnitzii (FP), a group subjected to sleep deprivation (SD), and a group experiencing sleep deprivation with Faecalibacterium prausnitzii colonization (SD + FP). The outcome indicates the average value plus or minus the standard error. *, p < 0.05; **, p < 0.01 compared with the control group. ns, non-significance.