Table 4.

Antimicrobial activity of Punica granatum.

Punica granatum Formulation	Effect	Model	Material	Dosage/Concentration	Mechanism	Study
Peel extract	Antifungal activity	Induced oral candidiasis	Wistar rats	125 µg/mL, 250 µg/mL, 500 µg/mL	Inhibition of C. albicans growth	Bassiri- Jahrom et al. [24]
Peel and seed extract	Antibacterial activity	Measuring of MIC and MBC, time-dependent growth inhibition assay	MRSA strains	1.25 mmol/L	Delay of initial growth of MRSA	Hussein et al. [25]
Peel extract	Antibacterial and antifungal activity	Diffusion disc method, broth microdilution method	Various types of pathogens	2.7 mg/mL	Inhibition of growth of different Gram-negative and Gram-positive bacteria and fungal pathogens	Kupnik et al. [26]
Methanolic flower extract	Antifungal activity in treating chronic dandruff	Clinical trial	Human subjects	28.1% (w/w)	Antioxidant activity, anti-itching and anti-inflammatory (inhibition of COX, LOX and PLA2)	Sahraie-Rad et al. [27]