Table 2.
Adverse events occurred during specific intervals (expressed as a percentage of the total number of patients on treatment during that specific interval).
| Side Effect | Baseline–24 Weeks (N = 76) (%) |
24–48 Weeks N = 27 (%) |
48–72 Weeks N = 24 (%) |
72–96 Weeks N = 21 (%) |
|---|---|---|---|---|
| Systemic Manifestations or Injection Site Events | ||||
| Fatigue | 50 | 51.8 | 66.6 | 61.9 |
| Headache | 47.3 | 62.9 | 58.33 | 76.1 |
| Dizziness | 81.6 | 74 | 75 | 76.1 |
| Fever | 63.1 | 48.1 | 45.8 | 33.3 |
| Nausea | 42.1 | 70.3 | 62.5 | 33.3 |
| Loss of appetite | 13.1 | 18.5 | 12.5 | 9.5 |
| Site injection reaction | 22.3 | 11.1 | 12.5 | 9.5 |
| Psychiatric Disorders | ||||
| Insomnia | 28.9 | 40.7 | 45.8 | 42.85 |
| Depression | 22.3 | 29.6 | 16.66 | 14.2 |
| Irritability | 30.2 | 40.7 | 50 | 52.3 |
| Musculoskeletal Symptoms | ||||
| Myalgia | 43.4 | 37 | 29.1 | 23.8 |
| Bone/joint pain | 22.3 | 22.2 | 20.8 | 14.2 |
| Skin or Hair Disorders | ||||
| Hair loss | 22.3 | 29.6 | 33.3 | 38 |
| Pruritus | 14.5 | 11.1 | 8.33 | 4.7 |
| Rash | 5.2 | 7.4 | 4.1 | 4.7 |
| Hematologic or Biochemical Reactions | ||||
| Neutropenia | 22.3 | 29.6 | 29.1 | 28.5 |
| Low platelet count | 19.7 | 25.9 | 25 | 28.5 |
| ALT increase | 6.5 | 11.1 | 12.5 | 14.2 |